Pseudomelanosis Duodeni

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Pseudomelanosis Duodeni

A 55-year-old male with history of coronary artery disease, chronic kidney disease stage 4, diabetes mellitus, uncontrolled hypertension (on multiple antihypertensive medications), and iron deficiency anemia was referred for esophagogastroduodenoscopy (EGD) for evaluation of intractable nausea and vomiting. EGD showed black speckled pigmentation of the duodenal mucosa (Figure 1). Duodenal biops...

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Pseudomelanosis Duodeni of Undetermined Etiology

Pseudomelanosis duodeni is a rare, benign condition of unknown etiology. It is characterized by collection of pigment-laden macrophages in the tips of duodenal villi. The pigment, originally interpreted as melanin, pseudomelanin, lipomelanin or hemosiderin, has now been demonstrated to be mostly ferrous sulfide. There is a strong association with chronic renal failure, arterial hypertension, di...

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Pseudomelanosis duodeni: a short review

Pseudomelanosis duodeni is characterized by the presence of brownish or blackish pigmentation in the duodenal mucosa identified during endoscopy. Although the pathogenesis is uncertain, it was generally believed that it is sequelae of luminal absorption of iron and sulfide chemicals, which is subsequently deposited in the lamina propria. It is often associated with hemodialysis and oral intake ...

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Gastrointestinal pseudomelanosis

An 81-year-old Caucasian woman with a history of hypertension, stage IV chronic kidney disease and iron defi ciency anemia was evaluated for a 3-month history of common bile duct dilation (16 mm). Physical exam was unremarkable with stable vital signs. Laboratory tests were signifi cant for a hemoglobin ranging from 8.4-10.0 g/dL (reference range: 12.0-15.0 g/dL) and creatinine ranging from 2.4...

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Charcoal-induced pseudomelanosis ilei.

outpatient department because of anal bleeding. She had been diagnosedwith ulcerative proctitis about 1 year previously and had experienced intermittent anal bleeding during treatment at a local clinic. She had no significant medication history and in particular had not used laxatives or oral iron. The initial colonoscopy revealed numerous variable-sized areas of black pigmentation in the mucos...

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ژورنال

عنوان ژورنال: Endoscopy

سال: 2005

ISSN: 0013-726X,1438-8812

DOI: 10.1055/s-2005-870144